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Research

The ANZBA Research Committee are facilitating, promoting and advocating for collaborative burn injury research and burn care research throughout Australia and New Zealand. Through collaborative research, we strive to improve the quality of burn care, and evidence-informed practice.

Current burn research studies being undertaking in Australian and New Zealand burn centres are listed below:

Principal InvestigatorEmail ContactTitle of StudyBurn Centres Inclusion CriteriaExclusion CriteriaSample SizeOutcomesCompletion DateOther Organisations
Dr Marcus Wagstaff & Tanja Klotzmarcus.wagstaff@sa.gov.auEvaluation of outcomes post treatment of burn scars with fractionated CO2 ablative laserRoyal Adelaide Hospital18+ adult burn patients with scar-associated complications for reconstruction with laser, convenience sample, prospective, any location, time post-injury varies greatlyinability to provide consent, active infections, previous radiation treatment, pregnancy or lactation, participation in another trial that may affect the outcome, complex locations, use of Accutane in last 6-12m, history of keloid formation.1>20Procedure details, demographics, skin type, ROM, MAPS, POSAS-O, POSAS-P, DAS, Dermalab measures: ultrasound for skin thickness, TEWL, colour, elasticity, TEWL with Vapometer.
Tanja Klotztanja.klotz@sa.gov.auDevices measuring transepidermal water loss of the skin: a systematic review protocol of measurement properties.Royal Adelaide HospitalStudies examining the reliability and measurement error of devices that measure trans epidermal water loss (TEWL)Studies which only report on TEWL outcomes.20-50Statistical reliability and measurement error, characteristics of study design.1/07/2021University of Adelaide
Nick Barrynicholas.barry@health.nsw.gov.auCold burns from cosmetic cryolipolysisRoyal North Shore Hospital,Concord General Repatriation HospitalPatient age >18 Burn sustained from cryolipolysis undertaken for cosmetic purposes.1>20 Burn TBSA %, Burn thickness, Length of stay, Theatre procedures, Time to heal5/05/2021
Ruilong Zhaorzha9073@uni.sydney.edu.auExternal validation of protein c as a prognostic marker in burnsRoyal North Shore Hospital,Concord General Repatriation Hospital18+, 10-80%TBSA, partial or full thicknesspregnant, activate local or systemic infection, other known coagulopathies50-100IV fluids, ICU LOS, LOS, number of surgeries, sepsis, mortality 30/06/2022
Nicola Claytonnicola.clayton@health.nsw.gov.auValidation of incidence and predictive factors for dysphagia in older persons following severe burn injuryidation of incidence and predictive factors for dysphagia in older persons following severe burn injuryConcord General Repatriation HospitalAny patient admitted to the Concord Burn Service over the age of 75 years with acute burn injury who is treated with the intent for survivalDay admission for surgical procedure only Palliative patients Non-burn admission (e.. nec fasc, TENS)50-100Primary: Functional Oral Intake Scale, Dysphagia related complications Secondary: Age, Gender, %TBSA burnt, Burn depth per percentage, BAUX score, Mechanism of injury, Past medical history, Duration of dysphagia treatment, Duration of enteral supplementation, Duration of oral supplementation, Hospital LOS, ICU LOS, Days of mechanical ventilation, Dependence on others for feeding, Surgical decision for conservative management, Number of surgical procedures requiring General Anaesthetic, Nutritional data, Days of bed rest, Days to mobilisation (from admission), Contributing new medical condition associated with burn, Living arrangement prior to admission, Discharge destination31/12/2022
Nicola Clayton nicola.clayton@health.nsw.gov.auClinical profile and recovery pattern of dysphonia following inhalation burn injuryConcord General Repatriation Hospital,The Alfred HospitalAll burn patients with suspected inhalation injury, Inhalation burn injury confirmed on nasendoscopy / bronchoscopy, ICU admission and intubation may form part of treatmentPrevious known laryngeal pathology, Previous known dysphonia , Patients whose voice function was not assessed due to poor prognosis for survival100+%TBSA burn, burn location and mechanism, Age, gender, duration of intubation, past medical history, ICU and Hospital LOS, Voice and laryngeal assessment, Duration of dysphonia, Treatment methods for dysphonia and laryngeal pathology 31/12/2021
Nicola Clayton nicola.clayton@health.nsw.gov.auRespiratory Muscle Strength Training (RMST) to facilitate swallow and pulmonary rehabilitation in critical care patients with severe deconditioning: a case seriesConcord General Repatriation Hospital1>20Swallowing endpoints as defined by Functional Oral Intake Scale, Flexible Endoscopic Evaluation of Swallowing (NZSS, PAS, Yale), Indirect Calorimetry, Peak Expiratory Flow, mechanical ventilation duration, ICU LOS, Hospital LOS.
Helen DeJonginfo@perthspc.com.auQuantifying scar maturation with multiple modes of ultrasound imaging – a cross sectional study.Fiona Stanley HospitalAdults attending the FSH Adult State Burns Outpatient Clinic at FSH with a burn injury. Assessing healed burn scars from 6 weeks post injury.Non healed scars/open wounds. Infectious scars.50-100 Ultrasound based scar thickness, echogenicity, Doppler and shear-wave elastography to quantify scar depth, density, vascularity and stiffness respectively. Also collecting burn depth, VSS, surgical intervention, time since injury, Fitzpatrick Skin Type and basic demographics. 1/12/2021Siemens Healthineers
Guy StanleyGuy.stanley@Gmail.comDelirium and skin biomarkers in burnsFiona Stanley HospitalAdultsUnable to consent50-100Delirium, Length of stay 30/06/2024
Dr Ashley Whitehornashley.whitehorn@adelaide.edu.auFacial burns management in Australia and New Zealand: A cross sectional benchmarking surveyRoyal Brisbane & Women’s Hospital,Queensland Children’s Hospital,Royal North Shore Hospital,Children’s Hospital Westmead,Concord General Repatriation Hospital,Middlemore Hospital,Waikato Hospital,Hutt Hospital,Christchurch Hospital,Royal Hobart Hospital,The Royal Children’s Hospital Melbourne,The Alfred Hospital,Adelaide Women’s & Children’s Hospital,Royal Adelaide Hospital,Fiona Stanley Hospital,Perth Children’s Hospital,Royal Darwin Hospital,Other Hospital SiteOne staff member (e.g. nurse, doctor) with relevant experience in facial burns management will be invited to participate in the survey.1>20Self reported survey responses28/06/2021JBI, University of Adelaide
Eduardo Deliyannised16630@bristol.ac.ukThe quality of burns websitesRoyal Brisbane & Women’s Hospital,Queensland Children’s Hospital,Royal North Shore Hospital,Children’s Hospital Westmead,Concord General Repatriation Hospital,Middlemore Hospital,Waikato Hospital,Hutt Hospital,Christchurch Hospital,Royal Hobart Hospital,The Royal Children’s Hospital Melbourne,The Alfred Hospital,Adelaide Women’s & Children’s Hospital,Royal Adelaide Hospital,Fiona Stanley Hospital,Perth Children’s Hospital,Royal Darwin Hospital,Other Hospital SiteNoneNone100+ Assessing the quality of first aid data Assessing the quality of factual information Using a scoring system for websites8/08/2021 Bristol University, University of Western Australia
Mark Fearmark@fionawoodfoundation.comUnderstanding the physiological and long-term health impacts of burn injury in childrenPerth Children’s HospitalPaediatric patientsIntentional burn injury, Presence of immunodeficiencies, Conditions where blood collection isn’t safe, Unable or unwilling to consent to specimen collection and storage, Diagnosed cognitive impairment, intellectual disability and/or mental illness, Nappy rash if urine collection requires urine bag100+routinely collected clinical dataUWA
Fiona Wood fiona.wood@health.wa.gov.auIMproving Psychosocial and Activity outcomes after Childhood burn Trauma (IMPACT study)Perth Children’s HospitalAll consecutive paediatric acute burn admissions Child 2 years or olderSignificant psychiatric morbidity in parent or social issues requiring professional psychosocial intervention postburn. Not able to read and understand the information. Unwilling to take part in the study. Comorbidities and/or injuries that influence ability to participate in physical activity measures50-100Basic clinical data, PedsQL, SDQ, CPSs, IWS-R (parents), Physical activity questionnaire, BBSIP31/12/2022
Dale Edgardale.edgar@health.wa.gov.auComparison of premorbid reported activity levels with post-discharge functional and quality of life outcomesFiona Stanley HospitalBurn Clinical Registry study. Adult burn patients >16Burn patients managed in ambulatory (outpt) mode100+LOS, number of surgeries, complications (ICD10 coded), Functional outcomes – Lower Limb Functional Index; QuickDASH  HRQoL – SF36; BSHS-B 24/12/2022Curtin University (School of Physiotherapy and Exercise Science)
Daniel Riciardello dricciardello@gmail.comFirework and sparkler burns in paediatric patientsChildren’s Hospital WestmeadJan 2004 – Dec 2019, Referred for burn related to firework or sparkler burns, Including those treated as inpatient and those treated in ambulatory care setting, Age <16Nil50-100gender, age, TBSA%, ICU admission, intubation, number of operating sessions, dressing/debridement, skin grafting, mechanism of injury, location of injury, adequacy of first aid (defined as cool running water for 20 minutes within the first three hours of the injury), presence of parental supervision, and mode of treatment.28/08/2020 ACI Statewide Burns Injury Service Network
Daniel Ricciardellodricciardello@gmail.comLaryngotracheal Stenosis Post Mechanical Ventilation in Paediatric Burn PatientsChildren’s Hospital WestmeadDec 2009 – Dec 2019, Children treated for a burn injury and required endotracheal intubation, Age <16If the endotracheal intubation was unrelated to their burn injury. 100+Age, gender, mechanism of injury, location of injury, %TBSA, number of days intubated.2/06/2021ACI Statewide Burns Injury Service
Madeleine Jacquesmadeleine.jacques@health.nsw.gov.auToo hot to handle? Full thickness burn injury in a child caused by cyanoacrylate glue and cotton – a case report and experimental studyChildren’s Hospital Westmead Literature review and Case Report of thermal injury from cyanoacrylate glue Nil 1>20Mechanism of injury, adequacy of first aid, %TBSA, depth of burn, surgery required (grafting), days until healing and scar management. 7/10/2020
Madeleine JacquesMadeleine.jacques@health.nsw.gov.auPaediatric exhaust contact burns in New South Wales – a ten year retrospective reviewChildren’s Hospital WestmeadAll exhaust contact burn injuries referred to the CHW burns service for consultation and management between Jan 2009 – Dec 2019, age ≤16 Nil100+Age, sex, home location, geographical treatment location, visits required at tertiary service, %TBSA, site of injury, mechanism of injury, days to healing, surgical intervention, scar treatment/management 31/12/2021The ACI Statewide Burns Injury Service
Jason Diab jdmisciali@gmail.comA licence to grill: charcoal barbeque burns in the paediatric populationChildren’s Hospital WestmeadJan 2010 – Jan 2019, All barbecue coal burn injuries in children <16 NilAge, Sex, %TBSA, Site of injury, Mechanism of injury, Season, Year, Admission Status, First Aid, Place of event, LOS, Number of Operations, Grafting, Complications
Jason Diab jdmisciali@gmail.comShisha-related burns: A paediatric case seriesChildren’s Hospital WestmeadJan 2009 – Dec 2019, All burn injuries <16Nil1>20sex, ethnicity, residential address, first aid location of injury, %TBSA, operative intervention, LOS, number of outpatient visits for treatment, infection and surgical complications.20/04/2021 ACI Statewide Burn Injury Service
Sonia Tran Sonia.Tran@health.nsw.gov.auHoliday hazards: burns in children during school holidaysChildren’s Hospital WestmeadChildren 5-16, Jan 2005 -Jan 2019, inpatients and ambulatory Nil 100+age, sex, mechanism of burn injury, place of injury, depth of burn, %TBSA, anatomical area, whether an inpatient admission was required, LOS, need for skin grafting, and complications16/03/2021 ACI Statewide Burn Injury Service
Madeleine Jacques madeleine.jacques@health.nsw.gov.auCyanoacrylate glue and cotton burns in children – A thirteen year retrospective reviewChildren’s Hospital WestmeadAll glue burn injuries, Jan 2007 – Aug 2020, age ≤16Nil1>20 Incidence of glue burns in the NSW paediatric population, classification of mechanism of injury (was exothermic reaction from glue and cotton recognised?), Time to healing, Requirement for surgical intervention, Ongoing scar treatment/management requirement31/12/2021 ACI Statewide Burn Injury Service
Cheri Templetoncheri.templeton@health.nsw.gov.auHand outcomes in children aged 1-5 years at 12 months post hand burn injuryChildren’s Hospital WestmeadChildren 12 mo – 5 years, <10% TBSA which involve a hand burn, A hand burn that requires skin grafting, Hand burns that take >14 days to heal that require at least 4 months of physiotherapy treatmentChildren that have partial or full amputation of a digit, Comorbidities such as rheumatoid arthritis, muscle or nerve conditions, moderate to severe developmental disability that would affect upper limb function/measurement of outcomes, Burns >10% BSA, Burns that healed in < 14 days, Parents unable to provide written informed consent50-100name, TBSA, burn distribution, age, gender, family socioeconomic status and child’s daily activities, date of injury, burn location, TBSA, depth of burn, mechanism of injury, surgical interventions and ongoing burn management, PDMS-2 score,. ROM flexion and extension/Contracture (goniometry) measurement31/12/2021 ACI Statewide Burn Injury Service
Andrea Mc Kittrick Andrea.McKittrick@health.qld.gov.auFeasibility, Acceptability and Safety of Vacuum Therapy on Burn Scar outcomesRoyal Brisbane & Women’s HospitalAdult patients aged >18 years, patients aged <18 years with parental consent, TBSA <15% treated with skin grafting scar present on a limbAge <18 years without parental consent, TBSA >50%, Pregnancy, Inability/unwilling to return for follow up, Inability to provide informed consent, Non-English speaking Patients with underlying medical or surgical history that is a contraindication to vacuum therapy, Scars to the face, neck or genitals20-50 Patient-reported outcome measures BBSIP, POSAS, EQ-5D-5L, Short Assessment of Patient Satisfaction (SAPS). Scar height (DermaLab ® series ultrasound), Sociodemographic details, hospital attendance, resource usage and intervention data and related costs, Data will be collected at baseline, 6 and 12-months post commencement of vacuum therapy. 31/12/2022
Andrea Mc Kittrick Andrea.McKittrick@health.qld.gov.auA systematic review to investigate outcome tools currently used for patients who have sustained hand burn injuries and to map the psychometric properties of the outcome measures identified from the literature using the International Classifications of Functioning, Disability and Health (ICF)Royal Brisbane & Women’s HospitalStudies were included if they reported assessment tools and outcome measures to determine hand function post severe burn injuries; published in English and available in their full-length. Studies related to a group <18 20-50A total of 25 outcome measures were confirmed for inclusion in this paper and each underwent further evaluation to identify their psychometric properties.The University of Queensland, Princess Alexandra Hospital
Andrea Mc KittrickAndrea.McKittrick@health.qld.gov.auA cross- sectional survey of health professionals across Australia and New Zealand to determine what outcome measures are important from a clinical perspective post hand burn injuryRoyal Brisbane & Women’s HospitalA cross-sectional study using survey design20-50 The University of Queensland, Griffith University
Leila Cuttle leila.cuttle@qut.edu.auThe use of biomarkers in children to predict healing potential and optimise burn wound careQueensland Children’s Hospital,Children’s Hospital Westmead,Perth Children’s HospitalOpportunistic recruitment of any paediatric burn patients undergoing a procedure whereby blister fluid or blood can be collected, patient age 0-16 yearsUnable to provide informed consent for recruitment100+ Patient demographics, Wound TBSA/depth/anatomical area/mechanism, first aid treatment, Time until wound re-epithelialisation, POSAS, BBSIP, VSS, scar ultrasound thickness, scar treatment, day post-burn sample was collected 31/12/2022 Queensland University of Technology, University of NSW, University of WA
Leila Cuttle leila.cuttle@qut.edu.auIncidence and risk factors associated with non-accidental burnsQueensland Children’s Hospital,Other Hospital SitePaediatric age 0-16, retrospective data analysis100+patient demographics, burn TBSA/depth/anatomical area/mechanism, time until presentation, first aid treatment, activity when burn occurred, burn intent, mortality or discharge date. 31/12/2021 Queensland University of Technology, Monash University (BRANZ)